Many Neurons fit the foregoing schema in every respect,, but there are also exceptions to most parts of it.. There are no neurons that lack a soma,, but there are neurons
that lack dendrites,, and others that lack an axon.. Furthermore,, in addition
to the typical axodendritic and axosomatic synapses,, there are axoaxonic
(axon-to-axon) and dendrodendritic (dendrite-to-dendrite) synapses..
The key to
neural function is the synaptic signaling process,, which is partly electrical
and partly chemical.. The electrical aspect depends on properties of the
neuron's membrane.. Like all animal cells,, the cell body of every neuron is
enclosed by a plasma membrane,, a bilayer of lipid molecules with many types of
protein structures embedded in it.. A lipid bilayer is a powerful electrical
insulator,, but in neurons,, many of the protein structures embedded in the
membrane are electrically active.. These include ion channels that permit
electrically charged ions to flow across the membrane,, and ion pumps that
actively transport ions from one side of the membrane to the other.. Most ion
channels are permeable only to specific types of ions.. Some ion channels are voltage
gated,, meaning that they can be switched between open and closed states by
altering the voltage difference across the membrane.. Others are chemically
gated,, meaning that they can be switched between open and closed states by
interactions with chemicals that diffuse through the extracellular fluid.. The
interactions between ion channels and ion pumps produce a voltage difference
across the membrane,, typically a bit less than 1/10 of a volt at baseline..
This voltage has two functions: first,, it provides a power source for an
assortment of voltage-dependent protein machinery that is embedded in the
membrane; second,, it provides a basis for electrical signal transmission
between different parts of the membrane..
Neurons
communicate by chemical & electrical synapses in a process known as
neurotransmission also called synaptic transmission.. The fundamental process
that triggers the release of neurotransmitters is the action potential,, a
propagating electrical signal that is generated by exploiting the electrically
excitable membrane of the neuron.. This is also known as a wave of
depolarization..
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