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All neurons are electrically excitable,, maintaining voltage gradients across their membranes by means of metabolically driven
ion pumps,, which combine with ion channels,, embedded in the membrane to
generate intracellular-versus-extracellular concentration differences of ions such
as sodium,, potassium,, chloride and calcium.. Changes in the cross-membrane
voltage can alter the function of voltage – dependent ion channels.. If the voltage
changes by a large enough amount,, an all-or-none electrochemical pulse called
an action potential is generated,,
which travels rapidly along the cell's axon,, and activates synaptic
connections with other cells when it arrives..
Neurons do not undergo cell division.. In most cases,, neurons
are generated by special types of stem cells.. A type of glial cell,, called
astrocytes (named for being somewhat star-shaped),, have also been observed to
turn into neurons by virtue of the stem cell characteristic.. In humans,, neuro
– genesis largely ceases during adulthood—but in two brain areas,, the
hippocampus and olfactory bulb,, there is strong evidence for generation of
substantial numbers of new neurons..
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